15p.zip -
While a standard .zip file uses the (a combination of LZ77 and Huffman coding) to find repeated patterns within a single stream of data, Genozip’s Deep method is domain-specific. It understands the structure of genomic data, allowing it to achieve compression ratios that general-purpose tools cannot match.
: It uses the BAM file's alignment data to "predict" the contents of the FASTQ files. Only the differences (residual information) between the two are stored. 15p.zip
Introduced in , the "Deep" method (triggered by the --deep command) is a novel approach to co-compression . How It Works While a standard