This episode marks a significant moment for Jessi's mental health arc. The Depression Kitty ( source ) represents the numbing, immobilizing nature of depression—portrayed not just as sadness, but as a "nothingness" that makes doing anything feel impossible.
Nick, Andrew, and Jessi travel through a magic portal in Nick's closet to the Department of Puberty. Nick is searching for a new Hormone Monster, while Jessi struggles with the heavy influence of the Depression Kitty.
Andrew remains preoccupied with his own hormonal urges, providing the episode's more graphic and comedic relief as he navigates the bizarre bureaucracy of the department. Major Themes
Nick’s journey through the department highlights his anxiety about "falling behind" his peers. He eventually meets Connie the Hormone Monstress , who becomes his new guide.
In the Season 2 finale of Big Mouth , titled the show takes a deep dive into the literal and metaphorical "world" of growing up. After Nick’s hormone monster, Tyler, is fired, Nick and his friends find themselves traveling into the supernatural dimension where all puberty-related chaos is managed. Episode Overview Title: The Department of Puberty (Season 2, Episode 10)