Changes in spine size are closely linked to LTP, a process that strengthens synapses over time.
Mechanisms of Synaptic Strength and Spine Size Regulation Reference: eLife 2023;12:e91566 1. Overview Download 91566
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Understanding how dendritic spines change size helps researchers decipher the brain's "wiring" and how it stores information. Disruptions in this structural plasticity are often linked to various neurological and cognitive disorders. The study investigates the role of specific proteins,
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The study investigates the role of specific proteins, including CaMKII (Calmodulin-dependent protein kinase II) and actinin , in managing the structural integrity and growth of the dendritic spine.
Download links * Insight. * Structural Biology and Molecular Biophysics. * CaMKII. * actinin. * long-term potentiation. * synapse.