: Enlarged fluid spaces in the deep white matter.
The Boston criteria version 2.0 for cerebral amyloid angiopathy : Enlarged fluid spaces in the deep white matter
The v2.0 criteria significantly increase diagnostic sensitivity—capturing more true cases without losing specificity—by broadening the biological markers recognized by MRI. : Enlarged fluid spaces in the deep white matter
: For the first time, white matter characteristics are part of the formal criteria. A diagnosis of probable CAA can now be made with just one lobar hemorrhagic lesion if accompanied by either: : Enlarged fluid spaces in the deep white matter
: While lobar intracerebral hemorrhage (ICH) and microbleeds remain central, cortical superficial siderosis (cSS) and convexity subarachnoid hemorrhage are now prioritized. Multiple separate foci of siderosis can now qualify a patient for a "probable CAA" diagnosis on their own.