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Shortness of breath, particularly during physical exertion.

A comprehensive update on HPS management and pathogenesis can be downloaded as a PDF from JHEP Reports . Download Syndrome hepatopulmonaire pdf

Increased shortness of breath when sitting or standing compared to lying flat. Shortness of breath, particularly during physical exertion

A drop in arterial oxygen saturation when moving from a supine to an upright position. A drop in arterial oxygen saturation when moving

While many patients are initially asymptomatic, those who develop symptoms often experience:

Non-specific markers like digital clubbing (swelling of fingertips), cyanosis (bluish skin tint), and spider nevi (spider-like veins) may also be present. Diagnostic Criteria Diagnosis is confirmed through the following findings: A Case of Hepatopulmonary Syndrome - PMC

Hepatopulmonary syndrome (HPS) is a serious pulmonary vascular complication that develops in patients with chronic liver disease or portal hypertension. It is defined by a classic triad: liver dysfunction, intrapulmonary vascular dilatations (IPVDs), and impaired arterial oxygenation.