Promiscuous and multivalent interactions between Eps15 ... - Nature

Are you interested in the of the protein?

In the bustling metropolis of the , a veteran gatekeeper named Eps15 stood watch at the terminal. He was the first line of defense and the architect of every delivery. 1. The Call to Action

A signal flared at the cell’s edge—the . Nutrients were waiting to come inside, but they couldn't just walk through the wall. They needed a specialized vessel. 2. Building the Network

As the cargo arrived, the membrane began to sag under the weight. Eps15 worked frantically, his "promiscuous" binding sites allowing him to hold multiple partners at once to keep the structure stable. He was the glue holding the early stage of the bubble—the —together. 4. The Final Pinch