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The study highlights that membrane binding involves a cooperative effort of multiple domains.

This guide focuses on the molecular mechanism of otoferlin-mediated vesicle docking and Ca 2+raised to the 2 plus power sensing in inner hair cells (IHCs). Role: Otoferlin acts as a key Ca 2+raised to the 2 plus power sensor for synaptic vesicle fusion in auditory IHCs. tm,cc,jp

Based on the 2025 research regarding the protein , which is crucial for hearing and synaptic transmission, The study highlights that membrane binding involves a